The CSIR has developed a novel, supercritical fluid-based encapsulation technology for encapsulation of sensitive actives such as probiotics.
Technology Field
Encapsulation technology
Technology Descriptiopen
The technology provides a method for encapsulating, and thereby protecting, an active substance, which may be especially sensitive or susceptible to harsh environmental conditions. Such substances include probiotics, which are often destroyed in the human gut before they reach the intestine where they should be active. The substance may also be proteins, such as vaccines, which are often destroyed during storage or inadequate cold chain management practice. The final product is an encapsulated product in particulate form.
The CSIR has a pilot scale production facility (which can be set up for GMP manufacturing), and patents in force in most territories including the USA and Japan, and still pending in some territories. There is a technology package ready for transfer.
The CSIR has formed a company together with the Industrial Development Corporation to commercialise the technology. There are good technical results supporting the probiotics application in terms of showing extended shelf life and improved survival through the gastric environment.
The Council for Scientific and Industrial Research, commonly known as the CSIR, is a world-class African research and development organisation established through an Act of Parliament in 1945. The CSIR undertakes directed, multidisciplinary research and technological innovation that contributes to the improved quality of life of South Africans.
The CSIR’s shareholder is the South African Parliament, held in proxy by the Minister of Higher Education, Science and Innovation.
CSIR vision
We are accelerators of socio-economic prosperity in South Africa through leading innovation.
CSIR mission
Collaboratively innovating and localising technologies while providing knowledge solutions for the inclusive and sustainable advancement of industry and society.
CSIR values
CSIR values statement:
Our beliefs, principles and the impact we wish to make to improve the quality of life of South Africans are EPIC. Team CSIR pursues Excellence, celebrates People, personifies Integrity, and welcomes Collaboration.
Our mandate
“The objects of the CSIR are, through directed and particularly multi-disciplinary research and technological innovation, to foster, in the national interest and in fields which in its opinion should receive preference, industrial and scientific development, either by itself or in co-operation with principals from the private or public sectors, and thereby to contribute to the improvement of the quality of life of the people of the Republic, and to perform any other functions that may be assigned to the CSIR by or under this Act.”
(Scientific Research Council Act 46 of 1988, amended by Act 71 of 1990)
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