The design of selective #HDACs inhibitors requires more exploration due to the multifunctional mechanistic nature of cancer and still remains a great challenge. Dedicating to this promising class of epigenetic anti-cancer drug targets, HDACs Targeted Library (https://bit.ly/3xdJLWw) were kindly prepared by Otava scientists.
The design of selective#HDACs inhibitors requires more exploration due to the multifunctional mechanistic nature of cancer and still remains a great challenge. Dedicating to this promising class of epigenetic anti-cancer drug targets, HDACs Targeted Library (https://bit.ly/3xdJLWw) were kindly prepared by Otava scientists. These are two receptor-based libraries which are specifically targeted towards class I and class II HDAC isoforms in such a way to minimize cross-reactivity between these two classes.
HDAC Class I Focused Library - 590 compounds
HDAC Class II Focused Library - 190 compounds
To order the libraries, please send your request directly toinfo@otavachemicals.com. All compounds are available from stock, cherry picking is possible.
HDACs are poly substrate enzyme involved in many biological processes, like cell proliferation, differentiation, apoptosis, and senescence. According to scientific reports, histone deacetylase inhibitors have shown their efficacy as inhibitors of cancer initiation and progression.
Otava Institute is a global provider of one-stop integrated research solutions for business and life science. Our team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for pharmaceutical, agro, cosmetic and material science industries.We are dedicated to providing clients with outstanding service in these key areas and will continue to push boundaries to remain an industry front-runner. Each day we expand our core competencies delivering of new technologies to meet all the customer’s needs.
Our location in Toronto Ontario, Canada provides our clients with the added advantage of North American IP rules and regulations and secure communication and logistics. Our Ukraine – based R&D facilities represented with the Ukrainian Laboratories, that is cooperating with leading Ukrainian research institutions and carries out research work in the format of outsourcing.
We work as a preferred partner to many of the world’s top 10 pharma firms, and hundreds of other companies, providing support with creative solutions for complex technical compound issues. Our scientific knowledge, combined with our research and manufacturing capability, enables us to support chemical processing and production without ever compromising on quality.
Our experience, dedication, and commitment to quality make us an ideal partner for discovery stage research.
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