PNA-Based Electrochemical Biosensors Development

In the development of PNA-based electrochemical biosensors, we first optimize the structure of the PNA and its solubility and other physical and chemical properties, and then fix the PNA probe without destroying the performance of the probe, and finally the signal generation mechanism is designed. Creative Peptides can help you scientifically and cleverly design and manufacture PNA-based electrochemical biosensors.

• We choose PNA as the active substance, which provides the possibility of ultra-sensitive detection of biosensors and strive to improve the poor solubility of PNA and low cellular uptake through structural modification
• We provide several methods for the immobilization of probes, including covalent binding, non-covalent binding, chemical adsorption and electrostatic adsorption.
• We can effectively convert hybridization events into electrical signals, and mainly provide two signal generation methods, including direct signals (oxidation of guanine or adenine) and indirect signals.