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Reconstruction of structures from their scattered intensity distributions is heavily exploited in a range of disciplines, with common methods limited when phase information is lost. Contemporary iterative algorithms depend on a priori knowledge of the object boundaries to solve such inverse scattering problems, but remain highly time-consuming and, at times, inaccurate. The proposed all-optical technology harnesses a digital degenerate cavity laser arrangement that registers the scattered intensity distribution only within the predefined boundaries of the object.
The process is ultra-rapid (nanosecond-scale) and bears very high spatial resolution potential.
Background and Unmet Need
Reconstruction of objects from their scattered intensity distributions stands at the basis of numerous medical and technological imaging procedures, including tomographic, seismologic, and single-shot X-ray imaging, speech recognition and radar detection. Such inverse scattering procedures are limited when phase information is lost in the process. In cases of objects with a compact support, this loss can be compensated for by using iterative algorithms that rely on a priori knowledge, such as the spatial features or constraints of the object of interest.
However, this approach is highly time-consuming.
The Solution
A novel all-optical phase-retrieval platform based on a digital degenerate cavity laser (DDCL) that incorporates both the intensities of the scattered light and the physical boundaries of an object, to provide a reconstructed image within 100 nanoseconds.
Technology Essence
The DDCL is comprised of a ring degenerate cavity laser, that includes a gain medium, two 4f telescopes, an amplitude spatial light modulator (SLM), an intracavity aperture, three reflective mirrors and an output coupler (Figure 1). When placed between the two lenses, the intracavity aperture, shaped in accordance with the compact support constraints, serves as a binary mask that filters out modes that fail to exhibit phase-dependence of their amplifications and losses. Integration of the specific scattered intensity distribution applied on the SLM, within the boundaries of the intracavity aperture, yields the most probable reconstructed object, which can be imaged through the output coupler onto the camera. The ultra-rapid phase retrieval process generates images that exhibit good agreement with the original object, including accurate replication of intensity (brightness) and phase (color code) distributions (Figure 2). The system demonstrated equally effective image reconstruction for objects of uniform, symmetric or asymmetric phase distribution.
Figure 1. Basic digital degenerate cavity laser arrangement for rapid phase retrieval
Figure 2. DDCL-reconstructed uniform (row 1) and random asymmetric (row 2) phase distribution objects (column c), showed good agreement with the intensity and phase distributions of the actual objects (column a).
Advantages and Applications
Advantages
Scalable
Applications
Development Status
We constructed a laboratory prototype and demonstrated with it reconstruction images composed of ~100 pixel with good quality within 100 nanoseconds. We have recently improved our optical design and interfaces so expect better performances. We incorporated computer pre and post processing to further improved the performance. We developed a real time concept that will not require a slow spatial light modulator.
Yeda ("Knowledge" in Hebrew) Research and Development Company Ltd. is the commercial arm of the Weizmann Institute of Science (WIS) and is the second company of its kind established in the world.
WIS is one of the world’s leading multidisciplinary basic research institutions in the natural and exact sciences. It is located in Rehovot, Israel, just south of Tel Aviv. It was initially established as the Daniel Sieff Institute in 1934, by Israel and Rebecca Sieff of London in memory of their son Daniel. In 1949, it was renamed for Dr. Chaim Weizmann, the first President of the State of Israel and Founder of the Institute.
Yeda initiates and promotes the transfer to the global marketplace of research findings and innovative technologies developed by WIS scientists. Yeda holds an exclusive agreement with WIS to market and commercialize its intellectual property and generate income to support further research and education.
Since 1959 Yeda has generated the highest income per researcher compared to any other TTO worldwide. Weizmann has generated a number of groundbreaking therapies, such as Copaxone, Rebif, Tookad, Erbitux, Vectibix, Protrazza, Humira, and recently the CAR-T cancer therapy Yescarta.
Yeda performs the following activities:
◣ Identifies and assesses research projects with commercial potential.
◣ Protects the intellectual property of WIS and its scientists.
◣ Licenses WIS' inventions and technologies to industry.
◣ Establishes new Startup companies based in WIS Intellectual Property
◣ Channels funding from industry to research projects.
Our portfolio covers a broad spectrum of the natural sciences, including:
◣ Agriculture and Plant Genetics, including Bio-fuels
◣ Chemistry and Nanotechnology
◣ Environmental Sciences and Solar Energy
◣ Mathematics and Computer Science
◣ Medical Devices
◣ Pharmaceuticals and Diagnostics
◣ Physics and Electro-Optics
◣ Research Tools
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