A method for the production of calcium phosphate nanoparticles loaded with jasmonate for the induction of defense mechanisms in plants has been developed. The resulting product allows a controlled release of methyl jasmonate, ensuring efficient and long-term protection.
Methyl jasmonate (MeJ) is a plant hormone involved in defense mechanisms, acting as an elicitor, in addition to participating in different plant development pathways. It is a natural and clean alternative to the use of pesticides. However, the low solubility, thermal stability and cytotoxicity of MeJ limits its application, and it can even become toxic.
To overcome these drawbacks, amorphous calcium phosphate (ACP) nanoparticles have been used, a biocompatible and biodegradable material that, once loaded with MeJ, protects the compound against thermal degradation, ensures prolonged retention thereof on the surface of the leaves, and allows a controlled release of the hormone. All this contributes to prolonging its action in the long term, guaranteeing a more efficient treatment in the field.
The preparation method comprises the formation of a precipitate of calcium phosphate nanoparticles, their subsequent suspension in an aqueous medium in which the MeJ is dissolved, with the adsorption of the molecule taking place on the surface of the nanoparticles. The resulting nanocomposite is stable for long periods of time and, furthermore, has shown less cytotoxicity than free MeJ.
Thanks to the use of these nanoparticles, the frequency of application could be reduced compared to current products, and contribute to the lower use of pesticides, generating a positive impact on many levels.
ADVANTAGES AND BENEFITS
Current development status
Laboratory prototypes
Applications
Biotechnology
Environment
Agriculture
Desired business relationship
Patent licensing
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