The technology of S.S.S. consists in its being an "Integrated System", it allows to perform studies in multiple combinations between the 5 cell lines of the kit, giving the possibility to obtain species-specific biological responses (Tursiops vs Grampus vs Ziphius) or family-specific (Delphinidae vs Ziphiidae) or tissuespecific (skin vs muscle).
Sea Sentinels System (S.S.S.) offers a kit consisting of 5 cell lines, obtained from tissues (muscle and skin) belonging to 3 species of marine mammals (Tursiops truncatus, Ziphius cavirostris and Grampus griseus); kept viable by cryopreservation and easily rearing in normal cell culture plates. The technology of S.S.S. consists in its being an "Integrated System", it allows to perform studies in multiple combinations between the 5 cell lines of the kit, giving the possibility to obtain species-specific biological responses (Tursiops vs Grampus vs Ziphius) or family-specific (Delphinidae vs Ziphiidae) or tissuespecific (skin vs muscle). S.S.S. is a multifunctional system for physiology, biochemistry, genetics and eco-toxicology studies, replacing the use of live animals.
Applications
Studies of physiology, biochemistry, genetics and ecotoxicology, Study of the effect of compounds on cellular processes, Toxicological and pharmacological research, Study of the consequences of changes in environmental conditions.
UniSMART - Fondazione Università degli Studi di Padova (Italy) is fostering collaboration between the University of Padova and external stakeholders.
It focuses on technology transfer, research-driven innovation, and postgraduate education. The foundation manages European projects, coordinates sponsored research, and offers innovation consultancy. It supports the commercialization of around 200 patent families, about third of which fall under life sciences and medical devices.
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