System for Automatic Pathology Detection & Categorization in Chest Radiographs

Summary of the technology

methods to provide automated segmentation of lesions and tumors, with minimal user interaction; the computerized algorithms will enable a reproducible measure, which is one of the most critical criteria for measurement; in addition, automated tracking over time will be developed. Given a new case, automated tools will enable the extraction of a previous case of the patient, based on which the current case can be analyzed more in context, and the abnormalities can be more accurately detected, segmented and measured.
Project ID : 8-2012-310

Details of the Technology Offer

Technology

The invention is a diagnostic aid for physicians to detect pathology in medical images.  Image features are represented as "visual words" and can then be classified and retrieved according to relevance for quick reference by the physician. The tool uses a stored dictionary of features to differentiate healthy from pathological tissues. 

Advantages

The rapid growth of computerized medical imagery using picture archiving and communication systems (PACS) in hospitals throughout the world has generated a critical need for efficient and powerful search engines to classify and search the visual data. In addition, the growing workload on radiologists in recent years increases the need for computerized systems which could help the radiologist in prioritization and in the diagnosis of findings.  The system was tuned to achieve high accuracy in diagnosis, with an average of over 90% correct classification on a publicly available database of 12,000 medical radiographs. In the ImageClef 2008 medical annotation challenge it ranked second. It is a highly efficient, with less than 200 milliseconds training and classification time per image.

Potential Application

In addition to being a diagnosis aid, the system is highly efficient as an image retrieval system based on desired criteria.  In the ImageClef 2008 image retrieval challenge it ranked first among all algorithms tested. Although the system has been applied to date on x-ray images, it can easily be adapted to other types of images such as ultrasound, MRI and CT.

Patents

US Patent pending

Project manager

Oren Calfon
Director, Business Development for high-tech & IT

Project researchers

Hayit Greenspan
T.A.U Tel Aviv University, Engineering
Bio-Medical Engineering

Related Keywords

  • Biological Sciences
  • Diagnostics, Diagnosis
  • Medical Technology / Biomedical Engineering
  • Biology / Biotechnology
  • Micro- and Nanotechnology related to Biological sciences
  • Industrial Biotechnology
  • Biobased Materials related to Industrial Biotechnology
  • Remote diagnostics
  • Micro- and Nanotechnology related to Biological sciences
  • In-vitro diagnostics
  • Agro and Marine biotech
  • Medical equipment
  • Electromedical and medical equipment
  • Medical instruments
  • Medical Devices and Diagnostics
  • Medical Imaging and Image Processing

About RAMOT at Tel Aviv University Ltd.

Ramot is Tel Aviv University's (TAU) technology transfer company and its liaison to industry, bringing promising scientific discoveries made at the university to industry's attention. The company provides the legal and commercial frameworks for inventions made by TAU faculty, students and researchers, protecting discoveries with patents and working jointly with industry to bring scientific innovations to the market.

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