- RAMOT at Tel Aviv University Ltd.
- From Israel
- Responsive
- Innovative Products and Technologies
Summary of the technology
EG30 for the treatment of Alzheimer's disease
Project ID : 10-2011-274
Details of the Technology Offer
EG-30: clinical phase drug for AMD and Glaucoma
EG-30 – the highlights:
· Excellent safety profile in healthy volunteers and glaucoma patients
•Low systemic exposure
•No increase in IOP in glaucoma patients treated with EG-30 for 16days (eye drops)
·Extensive safety and efficacy preclinical package:
•EG-30 inhibit the formation of amyloid beta oligomers and serve as a cytoprotectant agent
•Efficacy in dry AMD and glaucoma animal models
•Safety and toxicology including 6 months toxicology studies in rabbits and monkeys
·An FDA approved development path allowing a single confirmatory study for FDA approval of EG-30 for both glaucoma and dry AMD
·New derivatives for Alzheimer treatment