A customized, portable, on-site testing platform which utilizes LAMP technology, specifically enhanced by loop-primer endonuclease cleavage (LEC)–LAMP to address challenges such as Shiga toxin-producing Escherichia coli (STEC) and antimicrobial-resistant bacteria like CTX-M extended-spectrum beta-lactamase (ESBL) variants, which require innovative and adaptable solutions for field deployment. This breakthrough method enables the rapid, real-time detection of pathogens within 40 minutes. The technology is highly adaptable and holds the potential to provide single-base specificity in multiplex pathogen detection making it suitable for a wide range of applications including food safety, healthcare diagnostics, environmental monitoring, and agricultural biosecurity.
In today's rapidly evolving testing markets, the demand for fast, accurate pathogen detection is critical across sectors such as food safety, environmental monitoring, healthcare, and agriculture. Portable, molecular testing offers significant potential to deliver rapid on-site results enabling critical decision making in time limited situations.
Combining portability with extraction-free, LAMP-based detection represents a technological advancement which can deliver powerful, reliable sample-to-answer data transforming pathogen detection capabilities. Loop-Mediated Isothermal Amplification (LAMP) is the most used isothermal amplification technology due to its high specificity provided by primer design, tolerance to inhibitors and relatively short reaction time (<30mins). The technology is revolutionizing diagnostics with its rapid, reliable detection capabilities, crucial for food safety, environmental monitoring, healthcare, and agriculture. The global Isothermal Nucleic Acid Amplification Technology is estimated to be worth $4.4 billion in 2023 and poised to reach $6.8 billion by 2028, growing at a compound annual growth rate (CAGR) of approximately 9.2% from 2023 to 2028.
The versatile and portable LAMP-based testing platform developed by the University of Galway represents a significant advancement in on-site testing, offering industries a reliable and efficient tool for safeguarding product quality, ensuring regulatory compliance, and detecting contamination in a variety of settings. As industries increasingly adopt point-of-care and multiplex diagnostic solutions, this innovative platform offers a unique opportunity for industry leaders to enhance their pathogen detection capabilities, meet evolving regulatory demands, and stay competitive in a rapidly changing landscape.
Key sectors that stand to benefit include:
Intellectual property status
Patent already applied for
Patent application number : PCT/EP2020/069920
Where : Europe
Granted Patent
Patent number : US9944996B2
Where : US
Granted Patent
Patent number : US9745636B2
Where : US
Granted Patent
Patent number : AU2009256587B2
Where : Australia
Patent already applied for
Patent application number : US20110217703A1
Where : US
Current development status
Laboratory prototypes
Desired business relationship
Joint ventures
Technology development
New technology applications
Adaptation of technology to other markets
University of Galway has earned international recognition as a research-led university with a commitment to top quality teaching. Ranked Ireland's #1 university for sustainable development in the Times Higher Education World Rankings (THE), we're not just about excellence in teaching; we're about shaping a better world. Our commitment to sustainability is globally recognised, placing us 38th worldwide and in the Top 10 in Europe (THE). As a government SDG Champion and a leader in sustainability, we offer a learning environment that cares for you and our planet.
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