BREATHIFIC DENTAL SYNBIOTIC ORAL STRIPS

Here’s how Breathific works:

1) Place a Breathific oral strip on gums above upper molars.

2) Within 5 seconds it adheres discreetly and safely in the mouth… dissolving little by little, and time-releasing its probiotics so you swallow and ingest the strip and its probiotics slowly, instead of a few minutes like other oral probiotics.

3) A Breathific oral strip can last about 3 hours if you use one in the daytime, and up to 6 or more hours if you use one overnight (depending on your saliva flow rate and how muxh you fold or roll the strip).

4) Breathific’s probiotics (good bacteria) compete against oral pathogens (bad bacteria) for food, space, and resources, thus crowding out many oral pathogens… and promoting normal oral health while freshening breath naturally and helping to promote oral moistness.

• Saliva mixes with the strip and slowly creates a silky-smooth, edible gel.
• The gel coats your oral tissues and soothes your dry mouth and throat.
• NO RISK OF CHOKING -- Safe for use during sleep. Great for people who can't tolerate pills and lozenges.
• The strip gel may last from 3 hours to 6+ hours in your mouth before it's totally swallowed.
• NO MORE MORNING BREATH -- The probiotics will fight smelly germs.
• You'll sleep better and awaken with fresher breath and better oral health.
• You can use them during daytime as well.
• All natural, drug-free, dietary supplement, oral-dissolving strips adapt to oral irregularities, do not interfere with CPAPs, nightguards, or snoreguards.
• Safe for pets too.
• Imagine waking up with fresh breath and kissing your partner without embarrassment.
• Imagine the confidence of talking up close and personal to people without fear of breath odor.
• Think how you would feel when your next dental checkup is easier.

Some people are saying it helps with nighttime dry mouth and they can get better sleep because they are not waking up to drink water and use the bathroom.

This is not your usual oral probiotic that you merely chew up and swallow quickly … because oral probiotics do no good for your mouth when they are in your gut.

For oral probiotics to REALLY WORK, they must stay in your mouth more than 2.5 hours before being swallowed, and that’s what Breathific® does.

Unlike oral tablets or lozenges that you chew and swallow within a few minutes, Breathific® is an edible sustained-release oral strip that adheres discreetly in the mouth, slowly forms a gel with saliva, and is swallowed and ingested from three to 6+ hours, depending on saliva flow rate and use while awake or asleep.

As you slowly swallow the strip, this allows its probiotics to activate in the mouth where they have many oral benefits, before they are eventually swallowed and ingested to help the rest of the digestive tract.

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Breathific® Blue-Green Supplement Facts

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Breathific® Plain Color Supplement Facts

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Advantages over other oral probiotics:

• Only Breathific has patented, Place-and-Forget, synbiotic time-release adherent technology.
• Each strip contains billions* of organisms from three bacterial strains specially selected to promote oral health and to populate various oral niches before being swallowed for intestinal benefits.
  • (* 3.5 billion at time of manufacture and 1 billion at 18 months expiry)
• The strips have been formulated to safely and discreetly last in the mouth from three to 6+ hours. Nighttime saliva flow is about 50% of daytime saliva flow, so a strip lasts longer while sleeping.
• To achieve the most sustained release, you can roll or fold the strips. More folds or layers = longer sustained release.
• Because it's a strip, it's a great benefit for people who cannot swallow pills or are afraid of pills.
• Because of the time-release strip formulation, the probiotic organisms can rehydrate, adapt, survive, grow, colonize, and populate their specific oral niches for days or weeks instead of being swallowed down into the lower gut within 15 minutes like other oral probiotics.
• The strip also forms a soothing spreadable film that promotes oral moistness for relief of occasional dry mouth, such as during air travel, low humidity, mouth breathing, and wearing masks.

What Probiotics Do and How They Work

• Breathific adds billions of known good oral bacteria (probiotics) to your mouth.
• When used regularly, Breathific probiotics compete against bad dental bacteria (pathogens).
• Our probiotics are specially selected for their diversity, ability to fight bad oral germs, freshen breath, and promote normal oral health.
• Breathific probiotics release natural bacteriocins (natural germ-fighting compounds).
• Each strip contains patented, Place-and-Forget, time-release, adherent technology that allows you to “wear” the strip for hours at a time as it slowly dissolves.

Potential results¥ from using Breathific Strips:

• On your first morning — you'll notice fresher breath in the morning — no more morning breath when you use it while sleeping! This is worth millions alone! Your significant other will thank you…
• 1 day to 3 weeks— fresher breath all day, more confidence, whiter teeth, less plaque buildup, and hopefully a better love life due to all of the above
• Within six months — better dental checkups
• After a year — savings on dental treatment

¥ Everyone is different. Your results may vary. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Works Slowly In Your Mouth, Not In Your Gut

With its unique, patented, adherent, Place and Forget, film-forming feature, each strip time-releases into your mouth its strains of oral probiotics over three to six+ hours.

And because it adheres to your cheeks, gums, teeth, or oral appliances, you can even use it safely during sleep.

Other brands of oral probiotic supplements do not have this long-lasting ability.

Breathific’s intra-oral adherent strips stick discreetly in your mouth and slowly dissolve to form a spreadable probiotic film that is slowly swallowed and ingested over several hours. The film protects its oral probiotic strains and keeps them growing within your mouth where you need them most, before they are swallowed into your lower gut, where they may also be of benefit.

The probiotics spread throughout your mouth, then colonize and populate various oral niches before being swallowed. In these locations, many of the probiotic microbes continue to grow, replicate and compete against bad dental germs. They crowd out bad, odorous germs and fight them for space to grow. By growing good oral probiotic organisms regularly, you can eventually overwhelm bad oral germs, and re-balance your oral microbiome.

For many thousands of years, our ancestors used fermentation to safely preserve food. Every day they were exposed to probiotics in their food. However, today’s preservative methods tend to destroy microbes, including probiotics. Worse, our our modern day diet of fast foods, junk foods, and sugar lacks many probiotics, and tends to feed bad oral germs. Breathific Dental Synbiotic Oral Strips help to supplement some of the probiotics we need, especially for oral health.

Over time (3 months or so) with repeated use, healthy diet with fermented foods, and good oral hygiene practices, Breathific’s oral probiotics can help shift the population of microbes in your mouth toward better, friendlier microbes. More friendly oral microbes mean fewer bad bugs in your mouth, naturally. That’s because bad oral germs make bad odors. And fewer bad germs means fresher breath and a healthier mouth.

Breathific Dental Synbiotic Oral Strips are the first of a new class of multi-use, “Place-and-Forget“, adherent, oral synbiotic dietary supplements designed as a time-release oral strip.

A synbiotic is a combination of probiotics, prebiotics, and postbiotics.

• Probiotics are defined by the World Health Organization as “micro-organisms that confer a health benefit on the host when administered properly”. (We at RENUzORAL believe the proper way to administer oral probiotics is via an adherent, time release method.)
• Prebiotics are natural food fibers that are the preferred foods for the probiotics. Prebiotics keep the probiotics healthy in the strip before use, and during use while they are growing and doing their jobs.
• Postbiotics are the metabolic byproducts or components of probiotic microorganisms that have demonstrated beneficial effects on human health. They are often used as a more stable and convenient alternative to live probiotics. They include: short chain fatty acids, bacteriocins, exopolysaccharides, enzymes, and immune-modulating proteins.

“Place and Forget” adherence is the game-changing feature because it allows controlled-release of the strip's payload safely, while sleeping.

Morning breath is mostly caused by the nighttime overgrowth of bad oral germs. Most oral germs that cause gum problems smell bad.

By pitting good probiotic microbes against pathogenic microbes, we can crowd out and eliminate many bad oral germs. Fresh morning breath means that the good probiotics in Breathific are working.

Also — because of the well-known oral-systemic link***, we can help manage the link between oral problems and systemic problems by fighting bad oral germs. As the U.S. Surgeon General said, “You cannot be healthy without oral health, and oral health is integral with systemic health." Thus, fresher breath in the morning = fewer bad dental germs = healthier mouth = fewer links*** to systemic problems.

*** Oral health and systemic disease are intimately related but have remained, sadly, as isolated knowledge communities for decades. … it is noteworthy that bacteria form surface-attached communities on most biological surfaces, including the oral cavity. Biofilm-forming bacteria contribute to oral and systemic maladies. [Sintim HO, Gürsoy UK. Biofilms as “Connectors” for Oral and Systems Medicine: A New Opportunity for Biomarkers, Molecular Targets, and Bacterial Eradication. OMICS : a Journal of Integrative Biology. 2016;20(1):3-11. doi:10.1089/omi.2015.0146.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739346/]

Benefits*

(For verification of listed benefits, please see the references below and visit our Research Page)

* Disclaimer: There’s no guarantee of specific results, and your results can vary. However, please refer to the research reports below that support dental probiotics for oral health.

• Fresh breath in the morning and hours afterward
• Competes against germs that cause common oral conditions
• Soothes occasional oral irritations
• Moisturizes occasional dry mouth
• Safe for diabetics/pre-diabetics

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Breathific® Blue-Green Supplement Facts
Serving size : up to 2 strips
Servings per container: up to 10
Not a significant source of carbohydrates, sugars or dietary fiber ±
Calories: 0
RENUzORAL Dairy-Free Dental Synbiotic Blend* 30.38 mg¥Live Probiotics: 3.5 billion** CFU/strip:Limosilactobacillus reuteri 3.96 mg
S. salivarius BLIS M18® 13.21 mg,
S. salivarius BLIS K12® 13.21 mg,

(BLIS®, BLIS K12® and BLIS M18® are trademarks of Blis Technologies Limited)
Pre-and Post-biotics: Blue Agave Fiber, Konjac Fiber, Sodium Alginate, Pullulan, Acacia Gum, Locust Bean Gum, Tara Gum, Probiotic metabolites
Percent Daily Values Are Based On A 2,000 Calorie Diet
¥ Daily Value Not Established,
* Proprietary Technology of RENUzORAL®
** Total CFU at the time of manufacture, 1 Billion CFU at 18 months expiry±
Other Ingredients: Erythritol 100% Natural, Vegetable Glycerin, Natural Spearmint Flavor, Monkfruit Extract, Sunflower Lecithin, Microcrystalline Cellulose, Modified Cellulose Gum, Medium Chain Mono- and Diglycerides, FD&C Blue #1, Mono - and Dibasic Sodium Phosphate Buffers
May contain traces of starch.Contains no milk, sugar, wheat, yeast, gluten, nuts, soy, egg, shellfish.
Suggested Use: One to two strips per day or bedtime. Fold, roll, or cut strips for varied dissolutions. Place in mouth between gums and cheek. Adheres to gums in seconds, adapts to tissues, mixes with saliva to form a film, is swallowed and ingested within 6 hours. No refrigeration necessary. Store in a cool dry place. For ages 6 and up. Contraindicated in pregnancy and the immunocompromised.
Mfg. in Canada by ODF Nutra inc. for RENUzORAL, LLC,
Laguna Niguel, CA, USA
www.renuzoral.com
1-833-768-9725
U.S. Patent No. 11,690,801
‡These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

UPC# 867396000225
V 2.4 -- BLUE-GREEN COLOR Breathific® Dental Synbiotic Oral Strips
Fresh Breath
Dry Mouth Relief
Healthy Teeth & Gums
Use Asleep or Awake
Supports Oral Moisture
Lasts Up To 6 Hrs

10 EDIBLE STRIPS Mild MintDietary
Supplement
NET WT. 0.05 OZ (1.45 g)

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BREATHIFIC® Plain Color Supplement Facts
Serving size : up to 2 strips
Servings per container: up to 10
Not a significant source of carbohydrates, sugars or dietary fiber ±
Calories: 0

RENUzORAL Dairy-Free Dental Synbiotic Blend* 30.38 mg¥

Live Probiotics: 3.5 billion** CFU/strip:

Limosilactobacillus reuteri 3.96 mg

S. salivarius BLIS M18® 13.21 mg,
S. salivarius BLIS K12® 13.21 mg,
(BLIS®, BLIS K12® and BLIS M18® are trademarks of Blis Technologies Limited)

Pre-and Post-biotics: Blue Agave Fiber, Konjac Fiber, Sodium Alginate, Pullulan, Acacia Gum, Locust Bean Gum, Tara Gum, Probiotic metabolites
Percent Daily Values Are Based On A 2,000 Calorie Diet
¥ Daily Value Not Established,
* Proprietary Technology of RENUzORAL®
** Total CFU at the time of manufacture, 1 Billion CFU at 18 months expiry±

Other Ingredients: Erythritol 100% Natural, Vegetable Glycerin, Natural Spearmint Flavor, Monkfruit Extract, Sunflower Lecithin, Microcrystalline Cellulose, Modified Cellulose Gum, Medium Chain Mono- and Diglycerides, Natural Spirulina Pigment, Mono - and Dibasic Sodium Phosphate Buffers

May contain traces of starch.
Contains no milk, sugar, wheat, yeast, gluten, nuts, dyes, soy, egg, shellfish.

Suggested Use: One to two strips per day or bedtime. Fold, roll, or cut strips for varied dissolutions. Place in mouth between gums and cheek. Adheres to gums in seconds, adapts to tissues, mixes with saliva to form a film, is swallowed and ingested within 6 hours. No refrigeration necessary. Store in a cool dry place. For ages 6 and up. Contraindicated in pregnancy and the immunocompromised.

Mfg. in Canada by ODF Nutra inc. for RENUzORAL, LLC,
Laguna Niguel, CA, USA
www.renuzoral.com
1-833-768-9725
U.S. Patent No. 11,690,801

‡These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

UPC# 867396000232

V 2.5 -- PLAIN COLOR BREATHIFIC® Dental Synbiotic Oral Strips
Fresh Breath
Dry Mouth Relief
Healthy Teeth & Gums
Use Asleep or Awake
Supports Oral Moisture
Lasts Up To 6 Hrs

EDIBLE STRIPS Mild Mint

Dietary Supplement
NET WT. 0.05 OZ (1.45 g)

Current development status

Commercially available technologies

Finished technologies

Desired business relationship

Patent licensing

Joint ventures

New technology applications

Adaptation of technology to other markets

Other : veterinarian use for pets

Applications

for humans and pets to control dental problems