' Provides early detection of pancreatic cancer, significantly increasing the potential for successful treatment outcomes
' Utilizes targeted nanoparticles, enhancing specificity and reducing false positives in diagnostic imaging
' Supports the development of personalized medicine approaches by enabling precise lesion targeting
OVERVIEW
Georgetown University presents an innovative approach for the early detection of pancreatic cancer and precancerous lesions through biodegradable fluorescent polyplex nanoparticles (NPs). These NPs specifically target the Cholecystokinin-B Receptor (CCK-BR), offering a groundbreaking method for diagnosing pancreatic lesions in vivo. The targeted NPs can be conjugated with fluorophores or radioactive molecules, enabling the early detection of pancreatic intraepithelial neoplasia (PanIN) lesions, which are not visible through current imaging techniques.
BACKGROUND
Pancreatic cancer's late diagnosis results in low survival rates, highlighting a significant unmet need in the oncology market for early detection methods. This technology, with its potential for screening high-risk individuals and monitoring treatment responses, opens up considerable market opportunities in the diagnostic and therapeutic sectors of healthcare.
Benefit
●Increased Accuracy:Enhances the detection of early-stage pancreatic lesions, improving diagnostic precision.
● Non-invasive:Offers a safer, patient-friendly alternative to traditional diagnostic methods.
●Cost-Effective:Potentially reduces healthcare costs through early intervention and improved treatment planning.
●Versatile application, including diagnostic imaging and therapeutic agent delivery.
Market Application
●Diagnostic Imaging:For early detection and monitoring of pancreatic cancer.
●Personalized Medicine:As a tool in tailoring patient-specific therapeutic strategies.
●Pharmaceutical Research:In the development of targeted drug delivery systems.
Publications
US Published Patent Appln n.17/925,582
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