Seeking Technologies for Sampling Interstitial Fluid in Skin

Desired outcome

Interstitial fluid (ISF), the fluid in spaces between the cells, is a novel source of biomarkers that compliments conventional sources like blood and urine. The use of ISF for therapeutic drug monitoring, dermatological diagnoses and continuous biomarker measurements provides unique information and is potentially pain-free. Despite the advantages, ISF has received limited attention due to the lack of simple collection methods. Thus, there is a need for a simple ISF collection method.

The Procter & Gamble Company

Details of the Innovation Need

We need to access ISF to advance discovery of novel biomarkers related to skin health and whole-body health and enable us to use ISF for monitoring delivery/bioavailability of actives and sensing and demoing product efficacy (first use benefit).

WHAT WE ARE LOOKING FOR

Technologies Sampling Interstitial Fluid in Skin

Minimally invasive – No hypodermic needles or large instrumentation needed.

Simple – Allow for simple, point-of-care collection of ISF.

Quick – Collection can be done within minutes in clinic or at home.

Clean – Blood-free

Compliant – Safety and regulatory clearance for use

Flexible – Easy to be integrated with microfluidic, lateral flow, or electrochemical device.

WHAT WE ARE NOT LOOKING FOR

  • Tape strips, swabs, and other techniques that only sample stratum corneum.
  • Invasive techniques that involve blood.

Related Keywords

  • Biological Sciences
  • Biology / Biotechnology
  • Microbiology Technology

About The Procter & Gamble Company

An American multinational consumer goods corporation headquartered in Cincinnati, Ohio. P&G was founded over 180 years ago as a simple soap and candle company. Today, we’re the world’s largest consumer goods company and home to iconic, trusted brands that make life a little bit easier in small but meaningful ways. We’ve spanned three centuries thanks to three simple ideas: leadership, innovation and citizenship.

The Procter & Gamble Company

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There is no need to sign an NDA. You are not asked to reveal any confidential information nor provide any solution that is not protected at this point. You just have to provide non-confidential information. After submitting your proposal the posting company will evaluate it and directly connect with you. This is when if there is an interest you would request to sign a Non-Disclosure Agreement (NDA) with the company to keep the conversation ongoing.
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