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Innoventions Ltd. posted this:
Novel Emboli Capturing and Removal Double-Filtering System for Whole-Body Prevention of Embolic Complications During and After TAVI / TAVR ProceduresInnoventions' proprietary novel Emboli Capturing and Removal Double-Filtering System, integrated to TAVI/TAVR delivery system is for total double-filtration and collection of the embolic particles during the procedure and removing them from the body a the end of the procedure. Differing from the current emboli deflection devices which deflect the embolic particles for preventing cerebrovascular embolic complications, our device prevents dispersion of the embolic material and prevents them reaching all body organs. As such, with our device we are bringing a much more secure and effective solution than the currently used devices.Gerard SisóUniversitat Autonoma de Barcelona
Gerard SisóGEMMA-CIMITEC Group Research and Innovation Promoter at Universitat Autonoma de Barcelona
View ProfileGerard Sisó posted this:
Novel highly-sensitive microwave sensors for dielectric characterizationMicrowave technology is of special interest for the implementation of low-cost, low profile, and highly sensitive planar sensors devoted to the analysis of material properties. Microwave sensors exhibit a wide range of potential applications, in so many different fields such as health/veterinary (monitoring of electrolyte concentration in blood or urine), industrial processes (fermentation monitoring, liquid concentrations, cleaning processes monitoring…) or construction (defect detection in infrastructures), among others. The main characteristics that make this sensor technology competitive are the high sensitivity and the possibility of real-time monitoring, the latter being very important since it offers the chance to save time and resources that could be critical in some industries
GEMMA-CIMITEC Group Research and Innovation Promoter at Universitat Autonoma de BarcelonaMichael Locker posted this:
Novel KRAS G12C agent with improved potency & PK properties availableAgent being offered has almost 5x greater binding and 2.6x higher potency than AMG510. Additional data available upon sincere requests. Please contact me with serious interest only.
ShamRock PharmaceuticalsCSIC - Consejo Superior de Investigaciones Científicas posted this:
Novel luminescent probes of lanthanide complexes for sensing of biomoleculesCSIC and Universidad de Granada have developed a new family of antenna chromophores able to sensitize effectively luminescence of lanthanides to be applied as labelling probes for biomolecules. Industrial partners specialized in fluorescent probes for biological research are being sought to collaborate through a patent licence agreement.Universidad de Granada posted this:
Novel luminescent probes of lanthanide complexes for sensing of biomolecules.A research institution and a university from Spain have developed a new family of antenna chromophores able to sensitize effectively luminescence of lanthanides to be applied as labelling probes for biomolecules. Industrial partners specialized in fluorescent probes for biological research are being sought to collaborate through a patent license agreement.Sayali Warad posted this:
NOVEL METHOD FOR CRYO-PRESERVATION OF CELLS IN MONOLAYERSPreserves cells on a substrate and provides high post-thaw cell viability Cryopreserved cells are ready for immediate use for modeling human diseases, drug screening, research applications
IP Market Analyst at University of Alberta, Technology Transfer ServicesUniversidad de Alcalá-OTRI posted this:
Novel method for the detection of adulteration of saffron with gardeniaResearchers from the (Micro)-Separation Techniques Research Group of the Department of Analytical Chemistry, Physical Chemistry and Engineering of the University of Alcalá has developed a procedure for the detection of adulterations of saffron with gardenia based on the detection of geniposide by Liquid Chromatography with High–Resolution Mass Spectrometry detection. The procedure allows to detect adulterations with gardenia in an unambiguous and sensitive way. A problem not solved at present by any other existing methods. The group is looking for companies in the agro-food sector to sign technical cooperation agreements, commercial agreements with technical assistance or patent licensing agreements.Universidad de Alicante posted this:
Novel method to fabricate highly selective sensors for different substances of interestThe research group "Electro catalysis and Electrochemistry of Polymers", Department of Physical Chemistry at the University of Alicante has developed a novel method that allows highly selective electrode manufacture biometrics to detect any biochemical substance of interest, food or environmental. The method is based on the electro assisted deposit of molecularly imprinted silica layers on different electrodes. This allows a fast and efficient detection of the molecule of interest, independently of the other interfering. In addition, allows the regeneration of the electrode in a very simple way and lets its usage almost indefinitely. Innovative aspects The biometrical electrode manufacturing method is based on a electro assisted method of molecularly imprinted silica layers on different electrodes. With this new procedure, we obtain uniform and consistent layers of silica that allow highly selective detection of any biochemical substance of interest, food or environmental when these electrodes are used as amperometric, voltammetric, impedimetric and potentiometric sensors. Main advantatges of the technology The main advantage of the electro assisted deposit respect to conventional methods of thin film deposition (spin-coating or dip-coating), lies in the control of consistency and porosity of the layers. Due to the prevention of uncontrolled pore formation, avoids the indiscriminate passage of species from the solution to the electrode surface, reducing the interference in the detection of the analyte of interest. It has a high specificity and affinity for the molecule of interest. High control on the deposition of silica when is done by electro assisted mode. The possibility of varying the thickness of the silica layer and layer morphology allows for a highly consistent and reproducible layer. Electro assisted deposit method is capable of "self-healing", i.e. prevents the formation of holes in the assisted layer that interfere with the detection of the molecule of interest. With continued use, the sensor loses its effectiveness by the collapse of the pores with the species to be determined. In this case, the regeneration process is very simple: just repeat the procedure for removing the template molecule to be performed after the gel layer (electrochemical extraction or cleaning solvents). Thus, the pores of the sensing phase are released for use again.Universidad de Alicante posted this:
Novel method to increase production and extraction of phytosterolsThe research group "Proteomics and functional genomics of plants of the University of Alicante has developed a new procedure that increases the production and extraction of phytosterols in plant cell cultures in vitro. To do this, is added to the culture medium cyclodextrins and optionally methyl jasmonate. After growing under certain conditions, phytosterols are obtained with yields higher than the current extraction techniques from the plant material. This method allows a stable production of phytosterols, independent of geographical, seasonal and environmental factors, with reduced spaces requirements and easier process of purification and industrial scaling. The group is looking for companies interested in acquiring the technology for commercial exploitation. Innovative aspects Nowadays, the classical method of extracting phytosterols from vegetable raw materials has a very low yield. This, combined with the large amount of plant material needed to extract a significant amount of phytosterols from global natural sources (only could be supplied 10% of Western populations), causes a high cost of these products. With this new process of in vitro plant cell culture, it is possible to increase production and efficiency of extraction of phytosterols from natural resources for a greater percentage of the population that could benefit from the positive effects of phytosterols on health.Universitat Politècnica de Catalunya - UPC posted this:
Novel motion nanosensor based on mechanical amplificationIn the past years there is an increasing interest to incorporate in any electronic device a motion sensor to provide interaction: measuring our reactions, position or motion. Therefore, the motion sensors should be low-cost but more precise. A nanosensor based on a motion amplifier mechanism is presented. The design can amplify extremely small displacements (nanometers) up to 200 times. Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought.Universidad de Alicante posted this:
Novel procedure for polymeric foams with various applications from waste plastics.The research group "Processing and Pyrolysis of Polymers", Department of Chemical Engineering at the University of Alicante has developed an innovative process that allows recycling of different types of plastics (EVA, polyethylene, polypropylene, polyurethane, polymer melt, foam, rubber or any combination thereof) to transform in a simple and economical ways products with applications in various industrial sectors. The group is looking for companies interested in acquiring the technology for commercial exploitation. Innovative aspects The inclusion of waste plastic (EVA, polyethylene, polyurethane, polypropylene, polymer melt, foam, rubber, etc. Or any combination thereof) in the composition, permits its recycling in a simple and cheap, and that current procedures are difficult and very expensive. Together with a chemical foaming and dispersion of ferrites in the composition, applies the energy necessary for the cohesion of the materials by microwave. Ferrites dispersed in the mixture capture and transmit microwaves heat required for foaming in every part of the obtained mass. With this new procedure, getting pieces of great uniformity, stability and thickness that determines the user (up to 25 cm. in diameter) at a low cost and quick way.Innovation APTA posted this:
Novel Pseudomonas Strain for the Treatment of Iron-Deficient SoilProduction of pyoverdine,a type of siderophore, applicable as biofertilizer to reduce iron deficiency and the chlorosis induced by it. it also demonstrated an increase in plant growth due to higher iron bioavailability. Siderophores can act as efficient activators of induced systemic resistance systems in plants, as well as protect the plant from different pathogens.
Innovation Analist at Hub APTAFundacion Miguel Servet - NavarrabiomedFundacion Miguel Servet - Navarrabiomed
Fundacion Miguel Servet - NavarrabiomedNot defined
Fundacion Miguel Servet - Navarrabiomed posted this:
NOVEL SARS-CoV-2 VACCINE CANDIDATES WITH ENHANCED EFFICACY AND SAFETYCurrent vaccines to protect against SARS-CoV-2 rely on the immunogenicity conferred by the viral Spike protein, the main viral target against which the elicitation of neutralizing and protective antibodies is intended through vaccination. The Spike presents an extremely high affinity for the human ACE-2 (Angiotensin Converting Enzyme-2) receptor, which has been reported to be expressed in diverse layers of the organism, such as the epidermis, endothelium, muscle and sweat glands. Such a strong affinity between both proteins, the Spike and ACE-2, might lead to the retention of the immunogen and a suboptimal distribution to reach the lymph nodes, key for a robust immune response. Thus, we propose modifications in the SARS-CoV-2 Spike vaccine protein that reduces the affinity for ACE-2 while preserving key epitopes for elicitation of neutralizing antibodies. This technology lies in minimal modifications of the Spike protein sequences that reduce ACE-2 binding, leading to the aforementioned proposed advantages at the immunological level in this new vaccination strategy. To date, accurate biochemical experiments to show a reduced ACE-2 binding capacity for our vaccine candidates have been carried out to demonstrate the viability of the proposed solution, the results of which have been surprising in terms of confirming the initial hypothesis.Universidad de Alicante posted this:
Novel self-expanding polyurethane foams intended for inert filling of pleural and other human cavities.The Adhesion and Adhesives Laboratory of the University of Alicante has developed a new polymeric foaming material for in-situ filling and sealing of internal irregular different shaped human cavities, intended for patients suffering chronic pleural cavities and in-field injuries caused by bullets or accidental event leaving open blood vessels. The new foam is composed of two separate liquid components that can be mixed in a two-body syringe in such a way that the foaming time can be modulated for allowing the foam formation at the end of the syringe needle. The new polymeric foam can self-expanded and self-modelated for avoiding complications in open internal cavities caused by infections, blooding, fistulae, dyspnea or sepsis. The new foam is easily applicable, safe for biological tissues, and its use avoid the use of the current aggressive treatments in pleural cavities. It is looking for companies interested in acquiring this technology for its commercial exploitation.Universitat Politècnica de Catalunya - UPC posted this:
Novel sensor for in vivo nano-mechanical characterizationA nanoforce sensor has been designed to be able to work in aqueous environments. The system is based on a motion amplifier mechanism that allows to amplify extremely small displacements (nanometers) up to 200 times, providing the possibility to characterize the mechano-transduction mechanisms either of a single cell or a tissue in a 3D gel scaffold. Partners to further develop the system applying to specific assays and/or to establish commercial agreements along with technical cooperation are sought.Universidad de Alcalá-OTRI posted this:
Novel Synchronization Process for Multi-carrier or Single-carrier CommunicationsThe research group “Communications, Multirate Systems, and Biomedical Engineering” of the University of Alcala presents a novel synchronization procedure for multicarrier or single carrier systems for narrowband and broadband communications. This procedure allows a precise estimation of the symbol timing offset (STO), and a coarse estimation of carrier frequency offset (CFO). The procedure is based on the inclusion of symmetric extensions in the transmitted symbols for the synchronization, which makes it useful not only for communications systems based on the discrete Fourier transform, but also for transceivers based on the discrete cosine transform (DCT). Among its main applications are communications through single-mode optical fiber, powerline communications, wireless and wireline systems, and in general, all the techniques that use multicarrier and single carrier modulations. The group seeks companies from the telecommunications sector to sign technical cooperation agreements, commercial agreement with technical assistance and patent licensing agreements.Universitat Politècnica de Catalunya - UPC posted this:
Novel syringes and concepts for homogeneous injection of bone cementsNovel syringes and concepts useful for homogeneous injection of ceramic bone cements have been patented and developed. These new designs solve the current problems related to the press-filtering that limit the clinical applications. Partners to further develop the technology and/or to establish commercial agreements along with technical cooperation are sought.PhD Isabel Gavilanes-Perez posted this:
Novel technology affordable for developing new stretchable opto-mechanical devices with larger mechanical tunability, versatility and sensitivityResearchers from Spanish National Research Council (CSIC), Catalan Institute of Nanoscience and Nanotechnology (ICN2-BIST), Biomedical Research Centre Network (CIBER) and Catalan Institution for Research and Advanced Studies have recently developed the first stretchable plasmonic enhanced wrinkled Fabry-Perot cavities showing extremely high sensitivity to mechanical deformations. This novel technology enables developing new stretchable opto-mechanical devices with higher mechanical sensitivity, tunability and versatility. Manufacturers in the field of sensors for detection of mechanical deformations, pressure or forces are being sought to collaborate and/or exploit the existing know-how through a patent license agreement.
Open Innovation Manager at Spanish National Research CouncilFabiola Moreno posted this:
Novel Therapeutic Agent to Target Microbial BiofilmsA naturally produced signaling molecule combats chronic and resistant hard-to-treat infections and contaminations by inducing microbial biofilms to disperse.
Technology Licensing Assistant at Binghamton UniversityCracow University of Technology posted this:
Novel transparent polymer nanocomposites based on PMMA and inorganic semiconductor nanoparticles for optoelectronics applicationsA method of preparing novel and transparent polymer nanocomposites based on a polymeric matrix of polymethyl methacrylate (PMMA) and the inorganic nanoparticles of zinc sulfide doped with manganese atoms (ZnS:Mn).University of Szeged posted this:
Novel types of C-3 substituted kynurenic acid derivatives with improved neuroprotective activityNeurodegeneration may occur when the brain is exposed to high level of reactive oxygen species, mitochondrial dysfunction, neurotoxicity, such as excitotoxicity. Administering neuroprotective agents can prevent the chronic conditions damaging nerve cells. Therefore, there is an urgent need to develop effective neuroprotective agents.Universidad de Alicante posted this:
Novel visual inspection system for quality control in production procesessVisual inspection systems are based on the employment of pictures, both in the visible and infrared or ultraviolet spectrums. They can also make use of sonar images or adding structured light to the environment in order to analyze defects and shapes in products. The figure shows an image obtained by means of a range camera that allows distinguishing an object by its depth. Thus, its position and defects can be determined through its volume. The technology is totally developed and has been laboratory and field tested, although, it requires a particular specification for each case. The technology can be used for real-time inspection of production processes, both for the recognition and for the classification and quality inspection.Hygea Salud y Nutrición posted this:
Nutritional software which makes automatically personalized diets.Vitadieta is a system of Medical Nutrition Therapy, which makes automatically personalized diets for a wide range of goals (lose weight, healthy diet, sports nutrition, pathologies...). The system could be integrate inside a third-party software, or works online. Vitadieta offers functionalities of cross-selling oriented to franchises, recomending product and services of each franchise with the diets.CSIR posted this:
Nutritious South African organic vegetable drinkAn affordable, nutritious organic vegetable drink containing indigenous South African plants. It is an instant sorghum based dry pre-mix containing milled vegetable ingredients and is available in vanilla, chocolate and strawberry flavours.
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Luxembourg Institute of Science and Technology (LIST)Luxembourg Institute of Science and Technology (LIST)
Luxembourg Institute of Science and Technology (LIST)Research Institute
Luxembourg Institute of Science and Technology (LIST) posted this:
Observatory for Climate, Environment and BiodiversityThe Observatory for Climate, Environment and Biodiversity (OCEB) is a multidisciplinary team of researchers and engineers who push the state of the art in monitoring and assessing various components of the Critical Zone from the top of the trees down to the groundwater. The Critical Zone is the Earth's thin surface layer where rock, soil, water, air and living organisms interact with each other. With its cutting-edge technological infrastructures and monitoring networks, the OCEB offers a wide range of services and leverages expertise and knowledge to produce science-based evidence for supporting policy-making processes towards sustainable and informed management of natural resources.UNIVERSIDAD DE BURGOS posted this:
Obtaining amines from nitrocompounds through an effective, economical and sustainable processA research group from the University of Burgos has developed a new procedure that allows transforming nitro groups (1) to amines (2) in short times and with yields that reach 95%. The key to this transformation lies in the molybdenum catalyst used and the reducing agent.CSIC - Consejo Superior de Investigaciones Científicas posted this:
Obtaining of food-grade natural prebiotic oligosaccharides by enzymatic synthesis from disaccharidesCSIC has developed an enzymatic synthesis procedure of lactosil-fructosilated derivatives obtained from natural disaccharides. Lactosil-fructosilated derivatives are prebiotics potentially usable in healthy food compositions to prevent diseases of the gastrointestinal system. Looking for food or pharmaceutical companies to develop and produce the compound under patent license. An offer for Patent LicensingUniversidad de Alicante posted this:
Obtaining potent antioxidants from mulberry cell culturesThe Plant Proteomics and Functional Genomics group of the University of Alicante, in collaboration with the Institute of Integrative Systems Biology of the University of Valencia, has developed the technology of plant cell cultures of the genus Morus to obtain stilbenes. The innovation lies in the simultaneous use of two elicitor compounds to promote their production. With this technology, trans-resveratrol and trans-oxyresveratrol are obtained in high quantities, with the possibility of using them in the pharmaceutical, cosmetic and food industries thanks to their powerful antioxidant character. Companies interested in acquiring this technology for its commercial exploitation through patent licensing agreements are sought.Jorian Bos posted this:
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