Technology Offers Site map description
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Yeda posted this:
A Platform for Boosting Efficiency of Therapeutic RNA EditingSingle-point mutations can give rise to a wide spectrum of genetic diseases. Recent therapeutic approaches aim at editing the mutated mRNA, providing a safe, reversible and tunable treatment. However, these methods are currently not efficient due to knowledge gaps in the understanding of the rules determining RNA editing. Here we provide a powerful method to enhance the efficiency of RNA editing for treating genetic diseases associated with single-point mutations.
IMIM Institut Recerca Hospital del MarIMIM Institut Recerca Hospital del MarIMIM Institut Recerca Hospital del Mar posted this:
A prognostic and predictive serum biomarker in Small Cell Lung CancerPeripheral blood and its components (serum, plasma, and circulating cells) is an easily accessible fluid. An ELISA-based system that exploit circulating protein biomarkers found in this medium is more convenient to the patient compared to a more invasive lung biopsy. The researchers have found that high levels of serum hepatocyte growth factor (sHGF) protein in patients with SCLC shows clearly predicted for shortened survival and an incremental risk for death. HGF is a natural ligand for the oncogenic epithelial transition factor (c-Met) transmembrane tyrosine kinase receptor and serum HGF could be predictive of individual responses to new anti-cancer drugs: the Met inhibitors. The Met inhibitors are targeted therapies against c-Met receptor that are currently in development for the treatment of other neoplasms and are planned to be evaluated in SCLC. Therefore, a biomarker of prediction of response to these new Met inhibitors would be crucial for correct selection of patients for the clinical trials. Incorrect selection through other biomarkers in NSCLC has leaded to lack of benefit from these drugs in already performed phase 3 clinical trials, stressing the relevance of correct patient selectionUNIVERSIDAD DE BURGOS posted this:
A promising organic compound for redox flow batteriesIn the search for organic compounds for redox flow batteries, researchers from the University of Burgos have developed a synthetic procedure that allows obtaining a viologen, 3,3'-([4,4'-bipyridin]-1,1'-diio-1,1'-diyl)bis(butane-1-sulfonate), in a simple, selective and multigram scale. The use of this molecule can replace metals such as vanadium, giving as a result more economical and ecological batteries, among other advantages. Moreover, compared to other viologens, batteries built with the compound developed at UBU have a superior stability.
Cracow University of TechnologyCracow University of TechnologyCracow University of Technology posted this:
A propulsion/drive system of aquatic vessels.Both proposed side fins drive systems have similar features which are realized by slightly different mechanisms dependant on the room inside vehicles hull. Those features are as follows: - multi-functionality, - ability to generate an extra driving force, - significant increase of swimming speed, - reduction of robot unwanted hull movements during swimming with side fins enabling proper work of onboard equipment and sensors etc. (for solutions in robots imitating fish); - increasing the dynamic of swimming depth changes; - wide range of change of direction of thrust force (also reverse thrust). - unlimited range of change of thrust around axis of rotation of side fins, - ability to dynamically stabilize heel movement of the hull - no change in the direction of rotation of the main engine transferred into oscillatory motion of lateral fins, - less energy consumption, - frequency of oscillation at a level of several Hz
Unismart - University of Padua FoundationUnismart - University of Padua FoundationUnismart - University of Padua Foundation posted this:
A resilient and user-friendly CAPTCHAThis patented image-based CAPTCHA relies on user interaction because it depends on the innate human ability to recognize shapes in a confused environment.
Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC posted this:
A sea wave detector for improved autopilot systemsA new method for processing the signal from a speed log meter enables rapid and cost-effective wave detection, which in turn improves autopilot performance and provides safer operation in rough seas. We are seeking partners to further develop the system and/or to establish commercial and technical cooperation agreements.
Robert DiSilvestro posted this:
A seminatural ingredient drug for triglcyeride loweringA drug combination of 3 USA Generally Regarded as Safe (GRAS), seminatural ingredients is proposed for lowering plasma triglyceride (TG) readings (US and international patents pending). The ingredients are diet components, but have laboratory generated aspects. Some human and animal data exists for TG lowering of each ingredient, but the combination has not been tested. Compared to existing drugs, the newly proposed formula is relatively safe, cost effective, with a low pill burden. The envisioned product could be used alone and added to existing therapies.
Emeritus Professor, LLC President
Universidad de Granada posted this:
A simultaneous detection system of chromosomal alterations by sequencing, cytometry and imagingNew in vitro method to evaluate the presence of chromosomal alterations, particularly in 17q25. That applies three techniques combined (magnetic capture, flow cytometry and microscopy techniques) using a single specific DNA-labeled probe. The probe's multifunctional character opens the door to a powerful diagnostic, prognostic or monitoring kit for different types of cancer and diseases of genetic origin where these alterations are present.
INESC TEC posted this:
a single-stage, bidirectional and high-frequency isolated power conversion systemACDC Cube is a single-stage, bidirectional and high-frequency isolated power conversion system. ACDC Cube also uses a novel control method to do the interface between the Alternate Current (AC) distribution networks and a battery pack, or other Direct Current (DC) sources/loads, delivering higher power quality in a compact design. ACDC Cube has lower total volume and weight, increased durability and equivalent reliability when compared with a standard solution such as the voltage source converter plus dual active bridge. Due to its innovative features, ACDC Cube is especially suitable for applications where the size of the power conversion system is critical.
- Unismart - University of Padua FoundationUnismart - University of Padua Foundation
Unismart - University of Padua Foundation posted this:
A small molecule inhibitor of OPA1 GTPase activity with anti-cancer propertiesThe invention belongs to the field of research to improve the treatment of disorders such as cancer and cancer-induced angiogenesis involving the upregulation of the levels of the said protein OPA1.
Jingsen Ma posted this:
A Software Suit for Microbubble Enhanced HIFU for Noninvasive Ablations of Deep-seated TumorOur innovative software leads to a revolutionary breakthrough of non-invasive tumor ablations by enabling customized microbubble targeting ultrasonic therapies for deep-seated tumors in clinical setting, which works as a Virtual Lab for biomedical researchers, tumor Treatment Planning Software for therapist, and a design tool for HIFU manufactures to improve efficacy and safety of HIFU devices.
Vice President at Dynaflow, Inc.
- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
A Software System for the Microbial Source Tracking ProblemA Software System for the Microbial Source Tracking Problem
CSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones CientíficasCSIC - Consejo Superior de Investigaciones Científicas posted this:
A Sustainable Procedure to Released Bioactive Compounds from BiomassCSIC has developed a procedure to extract bioactive compounds from wet biomass, in example microalgae or/and seaweeds, by using a sequential methodology. The procedure is quick, selective, give high yields, maintain bioactivity and minimize the impact to the environment. Industrial partners from the chemical or pharmaceutical or food industry are being sought to collaborate through a patent licence agreement. An offer for Patent Licensing
Yeda posted this:
A Sustainable Process for Phenol ProductionPhenol is an important industrial commodity used as a precursor to many useful compounds. It is being utilized in huge amounts in a wide range of industry sectors including pharmaceuticals, plastic-related products production, paints & coatings, electrical equipment, foams and fuel additives. The current most prevalent method for phenol production is the three-step cumene hydroperoxide process that while established, has serious drawbacks related to safety, low selectivity in the formation of cumene hydroperoxide, low per pass yield and the formation of acetone as a byproduct. A new phenol production method developed at the Weizmann Institute of Science based on electrocatalytic oxidation of benzene, allows for simple, efficient, cost-effective and selective production of phenol. This new method can result in a drastic cost reduction that will further be emphasized in the future with the ongoing reduced need of the current process, byproduct, acetone. The method suggested here can also be applied in the future in other processes for conversion of arenes to the corresponding phenols
Sayali WaradUniversity of Alberta, Technology Transfer ServicesSayali Warad posted this:
A Sustainable SAGD Follow-up Steamless Enhanced Bitumen Recovery Approach Combined with Non-Condensable Gas and Waste Heat UtilizationCP-SAGD+ (Advanced Clean Power- Steam-Assisted Gravity Drainage) simultaneously generates power, extracts green bitumen, and sequestrates SAGD emissions for EOR and reservoir pressure support
IP Market Analyst at University of Alberta, Technology Transfer Services
Universidad Andres BelloUniversidad Andres BelloDror Elad posted this:
A testing platform for code written with GenAI (copilot, code wisperer, LlamaProvengo introduces - Active Software Requirements (based on formal methods), enabling specification, verification and validation of reactive, complex, highly regulated, or mission critical systems. A novel modeling platform, allowing users to map complete designs and specifications for reactive systems. We enable easy validation, verification of the requirements, eliminating ambiguity in the development and execution stages. By providing a holistic and executable map of all features, processes and system, Provengo helps you make sure the system is complete, all teams members clearly understand its intent, and all tests are mapped, prioritized to reduce operational risk Areas of improvement: Time-to-Market, development productivity, system completeness, reduce communication flaws, system ambiguity, race conditions, risk based testing, Test Driven Development (TDD), Behavioral driven development (BDD)
CEO at Provengo
- IMIM Institut Recerca Hospital del MarIMIM Institut Recerca Hospital del Mar
IMIM Institut Recerca Hospital del Mar posted this:
A TREATMENT FOR TRIPLE NEGATIVE BREAST CANCERTriple negative breast cancers are tipically associated with por prognosis, due to aggressive tumor phenotype(s), only partial response to chemoterapy and present lack of clinically established targeted therapies and respresent the focus of increasing interest at the clinical, biological and epidemiological level, as disclosed in Podo et al., Triple –negative breast cancer: Present challenges and new perspectives, Mol. Oncol., 2010, 4, 209-229. There is, thus, a particular need for new active agents suitable for breast cancer treatment, and in particular need for triple negative breast cancers. 
Covid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by InnogetUniversidad de Cádiz posted this:
A very innovative accessory element to distribute and redirect the air flow for split air conditioningBrisAire should be placed on the air exit located on the outside of the air conditioning, held to the casing using the two adhesive strips, which allow easy assembly and disassembly. The central piece, made of light material, makes it ideal for absorbing the mass of air, acting as a loading buffer. The openings in the central body of BrisAire are arranged in rows across the surface. Its particular provision aims to create an effect of irregular distribution of air flow in the room, preventing its impact directly and uniformly on the people in the room. Once placed on the air conditioning, the element standing by on the off position, it reassembles a paper bag, attached to the air conditioning by its wider sides, and the other two sides being unfastened. When the air conditioning is turned on, BrisAire will inflate releasing some air through the openings in its body and the rest via the unfastened side to the casing of the air conditioning. The openings and the two free sides, prevent the return of air to the equipment, which could cause defects in the efficiency of the apparatus. To prevent the air from the air conditioning impacting directly on the people in the room, BrisAire has larger openings on the top side which points upwards, while the smaller openings are found beneath.- Universitat Politècnica de Catalunya - UPCUniversitat Politècnica de Catalunya - UPC
Universitat Politècnica de Catalunya - UPC posted this:
A wireless Augmentative and Alternative Communication SystemThis new system is an Augmentative and Alternative Communication system (AAC) that allows people with language disabilities to communicate through icons without the intervention of external support. The design is formed by two low-cost separated blocks (selection of the symbols and voice reproduction) with a wireless communication, so it facilitates its scalability, to adapt it to user's vocabulary, and mechanical and intellectual skills. Partners to further develop the system and/or to establish commercial agreements along with technical cooperation are sought.
Jayita Bandyopadhyay posted this:
Access to worldclass laboratory, pilot-scale facilities, skilled personnel and technology portfolio.The Centre for Nanostructures and Advanced Materials integrates its knowledge of the market and unique set of capabilities including skilled personnel with knowledge in advanced materials (nanomaterials and polymer (nano)composites). Lab-scale R&D facilities, characterization and pilot-scale facilities, to offer holistic technology solutions to partners/clients in the chemical industry.
Principal Researcher at CSIR
Universidad de AlicanteUniversidad de AlicanteUniversidad de Alicante posted this:
Acid-base electrochemical flow battery (ABEFB)The research group of Applied Electrochemistry and Electrocatalysis of the University of Alicante has developed an electric energy storage system. This system uses neutralization acid-base free energy for discharge process (use as battery), while charge process is performed by inverting previous reactions. The electrodic reactions are hydrogen evolution and oxidation reactions so no net hydrogen consumption exists. The research group is looking for companies interested in licensing the technology, developing R & D projects to optimize this initial idea and/or to adapt this development to their needs for a future commercial exploitation of the patent.
Fabian BelinLuxembourg Institute of Science and Technology (LIST)Fabian BelinPartnerships Development & IP Valorization at Luxembourg Institute of Science and Technology (LIST)
Fabian Belin posted this:
Acidosis saver for efficient anaerobic digestionThe technology is based on bioaugmentation which consists of adding specialized microorganisms to biological systems to improve performances. The bioaugmentation in AD is done via a specific microbiome enriched in a unique Cloacimonetes organism which boost the AD process robustness and efficiency. Our microbial technology acts by quickly and efficiently consuming propionate and other VFAs present in the anaerobic reactors allowing to restart methane production (Figure 1).
Partnerships Development & IP Valorization at Luxembourg Institute of Science and Technology (LIST)
Universidad de Alcalá-OTRIUniversidad de Alcalá-OTRIUniversidad de Alcalá-OTRI posted this:
Acoustic propagation model and location systems for underwater environmentsGEINTRA, a research group from the Department of Electronics of the University of Alcalá, provides a model for studying the acoustic propagation in underwater environments. This model is useful for communications and positioning systems. The proposed model provides the channel response for the usual environmental phenomena. The model simulate how these phenomena affect a particular acoustic signal, and therefore, the performance of an underwater system based on acoustic signals can be evaluated previously to its deployment. The model has been tested for the case of underwater localization systems. GEINTRA is looking for companies working in telecommunications and IT sectors or performing works related to exact science and physics to achieve technical cooperation agreements.
Yeda posted this:
Acquisition of Multidimensional NMR Spectra in a Single ScanMultidimensional nuclear magnetic resonance (NMR) is used nowadays in many applications (e.g., discovering new pharmaceutical drugs, characterization of new catalysts, and investigation of the structure and dynamics of proteins). One drawback of this technique is that multidimensional NMR requires relatively long measurement times associated with hundreds or thousands of scans, in contrast to one-dimensional spectroscopic methods. Therefore, rapidly changing chemical systems and in vivo clinical measurements such as magnetic resonance imaging (MRI) are not suited for this technique. The current technology allows the acquisition of multidimensional NMR scans using a single continuous scan, thereby shortening the time needed to acquire high-quality MRI images. This technique could be applied to existing NMR/MRI devices.
USP Innovation AgencyUSP Innovation AgencyUSP Innovation Agency posted this:
ACQUISITION OF SELENIUM-ENRICHED YEAST BASED ON AGRO-INDUSTRIAL RESIDUESIntroduction: According to recent article published by Molecules Journal, selenium is one of the elements classified into the group of micronutrients indispensable to guarantee the proper functioning of organisms. In addition, over the last few years, many new discoveries come up about selenium potentialities in the animal and human diet, such as its power anticarcinogen. Considering the important nutritional rule of this component and the need of a production models more and more environmentally-friendly, the present invention describes a production process of selenium enriched yeasts based on agro-industrial residues, such as sugarcane bagasse and rice bran, which serve as carbon and nitrogen sources. Purposes: This innovative biotechnological production process uses agro-industrial residues as substrate, resulting in a biomass of yeast that contains high selenium levels. Animals, as know, obtain selenium mainly through the aliments; then, this biomass can be used as a component in the animal nutrition to improve its development, fertility, eggs quality, milk and meat. Furthermore, it can act as component in the prevention of many diseases, for example, cancer. Target Market: Agro industrial, Veterinary and Pharmaceutical Industries.Fundació URV posted this:
Acrylic thermosets prepared by dual curing at room temperature fit for coatings and adhesivesFormulations for the preparation of thermosets by dual curing, at room temperature in two stages, stable over time, from the reaction of amine compounds with 2 or more N-H bonds with a vinyl compounds with a minimum of 2 double α, β- conjugated bonds to carbonyl ester groups and further polymerization of vinyl groups in excess, with completely controlled characteristics of the material at the intermediate stage.
MP Lighting posted this:
Active cooling system for led lighting industryLight-emitting diodes (LED), like any semiconductor, emit heat during their operation. This is because of (75% – 85%) of electrical energy is converted to thermal energy which results in an increase in the temperature of the LED. Thermally stressed LEDs lose efficiency and their valuable technical parameters. That’s why we need to control the temperature of the LED.
- Covid-19 Innovation Challenges by InnogetCovid-19 Innovation Challenges by Innoget
Covid-19 Innovation Challenges by Innoget posted this:
Active Masks with Virus Neutralizing PropertiesActive Masks with Virus Neutralizing Properties Professors Willner and Pikarsky are developing masks and possible ventilation systems that will contain virus neutralizing properties. They have undertaken the development of matrices that neutralize pathogens which can be incorporated into fabrics, paper, or nonreactive particles such as silica or alumina. Project ID : 47-2020-10888
